Jurgen Klopp’s decision to move away from 4-3-2-1 to his favoured 4-2-3-1 formation coincided with the first defeat of his Liverpool tenure.
The German has James Milner and Jordon Ibe available after both returned to full training on Monday.
Milner could be fielded in the centre of the park or be shifted to the right at Ibe’s expense, though Klopp has plenty of options in midfield, with Philippe Coutinho, Roberto Firmino and Adam Lallana also vying for the positions behind Christian Benteke.
In defence, Dejan Lovren looks the obvious replacement for Mamadou Sakho, who is sidelined for a number of weeks with a knee problem, though the fit-again Kolo Toure is another option.
Klopp will make a late decision on Daniel Sturridge’s fitness – the striker has returned to full training but, given the length of his absence, is said to be short of being 100%. A role from the bench seems likely.
Elsewhere, Jordan Rossiter is close to full fitness, whilst Jordan Henderson could also be back in full training next week.
Joe Gomez, Danny Ings and Jon Flanagan remain long-term absentees.